摘要
综述了近年来米格列奈合成方法的研究进展,将米格列奈的合成方法分为不对称合成法、化学拆分法和手性源法,并对各个方法的优缺点和前景进行了比较。
Mitiglinide has been synthesized by several related methods which involve optical resolution,asymmetric synthesis and diasteroselective alkylation using chiral auxiliary. The advantage and disadvantage of the different synthetic methods were summarized and discussed, And their perspective were also discussed.
关键词
米格列奈
合成
mitiglinide calcium, synthesis, synthetic method
