摘要
随着经皮介入治疗技术的进展和直径小、压力高、顺应性低的长球囊的应用,膝下动脉经皮腔内介入血运重建成为具有广泛前景的介入新领域。经皮球囊血管成形术近期疗效和技术成功率高,目前被认为是处理膝下动脉狭窄最有效的方法,金属裸支架置入仅用于球囊扩张术后效果欠佳或者失败的补救手段。小规模临床研究提示Cypher雷帕霉素涂层支架置入膝下动脉在中、远期通畅率高,再狭窄率低,但仍需多中心临床研究的进一步证实。
With the development of intervention techniques and availability of ＂dedicated＂, long small-vessel balloons, the belowknee territory is thought of today as one of the most promising frontiers in the entire endovascular field. Percutaneous transluminal angioplasty is associated with high rates of technically success and limbs salvages, which is recommended as the first-line therapy for the infrapopliteal arterial stenosis. Bare-metal stent can be useful in the infrapopliteal arterials as salvage therapy for a suboptimal of failed result from balloon dilation. Small-scale clinical studies have indicated that Cypher sirolimus-eluting stent is a safe and effective long-term option for critical limbs ischemia due to severe infrapopliteal arterial disease. The sirolimus-eluting stent can lead to a high rate of long-term patency and low rate of restenosis, however, a muhicenter trial should further elucidate the role of drug-eluting stent in the treatment of the disease.
出处
《心血管病学进展》
CAS
2009年第1期27-29,共3页
Advances in Cardiovascular Diseases
关键词
膝下动脉狭窄
重症肢体缺血
经皮球囊血管成形术
雷帕霉素涂层支架
below-knee arterial stenosis
critical limbs ischemia
pereutaneous transluminal angioplasty
sirolimus-eluting stent
