期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

脂联素与冠心病及其危险因素的研究进展 被引量：4

Progress of Research in Adiponectin with Risk Factors for Coronary Heart Disease
下载PDF
导出
摘要 脂联素是脂肪组织特异性分泌的一种激素蛋白。研究表明,脂联素在冠心病发生和发展中起调控和保护作用并且在控制冠心病危险因素方面也起重要作用。现主要论述脂联素与冠心病及其危险因素方面的研究进展。 Adiponectin is a hormonal protein, which is secreted from fatty tissue. Research has shown that adiponectin is the origin for regulation and protection effect depended on occurrence and development of coronary heart disease besides made important effect to dirigate risk factors in coronary heart disease. To present archdissertation on progress of research into adiponectin with risk factors for coronary heart disease.
作者 金雄杰 李玉子
机构地区 延边大学附属医院心内科
出处 《心血管病学进展》 CAS 2009年第1期122-125,共4页 Advances in Cardiovascular Diseases
关键词 脂联素 冠心病 危险因素 adiponectin coronary heart disease risk factors
分类号 R541.4 [医药卫生—心血管疾病]
  • 相关文献

参考文献20

  • 1陈月.脂连素——新型的脂源激素[J].解放军医学杂志,2003,28(2):183-185. 被引量：17
  • 2Berg AH, Combs TP, Scherer PE. Acrp30/adiponectin : an adipocytokine regulating glucose and lipid metabolism [ J ]. Trends Endocrinol Metab, 2002,13 ( 1 ) : 84-89.
  • 3Yamauchi T, Kamon J, Minokoshi Y, et al. Adiponectin stimulates glucose utilization and fatty acid oxidation by activating AMP-activated protein kinase [ J ]. Nat Med,2002,8 ( 11 ) : 1288-1295.
  • 4Ohashi K,Ouchi N, Kihara S, et al. Adiponectin 1164T mutation is associated with the metabolic syndrome and coronary artery disease[ J]. J Am Coll Cardiol, 2004,43(7) :1195.
  • 5Hug C, Wang J, Ahmad NS, et al. T-cadherin is a receptor for hexameric and high-molecular-weight lorms of Acrp30/adiponectin [ J ]. Proc Natl Acad Sci USA ,2004,101 : 10308-10313.
  • 6Chinetti G, Zawadski C, Fmchart JC, et al. Expression of adiponectin receptors in human macrophages and regulation by agonists of the nuclear receptors PPARalpha,PPARgamma, and LXR [ J ]. Biochem Biophys Res Commun, 2004,314 (1):151.
  • 7Mallamaei F, Zoceall C, Cuzzola F, et al. Adiponectin in essential hypertension [ J]. J Nephrol,2002,15:507-511.
  • 8Valsamaki G, Chetty R, McTeman PG, et al. Fasting serum adiponectin concentration is reduced in lndo-Asian subjects and is related to HDL-C [ J ]. Diabetes Obes Metab ,2003,5 ( 2 ) : 131-135.
  • 9Utpal BP, Xueliang D, Terry PC, et al. Structure function studies of the adipocyte-secrered hormone Acrp30/adiponectin [J]. Biol Chem, 2003,278 ( 11 ) : 9073-9085.
  • 10Cnop M, Havel PJ, Utzsehneider KM,et al. Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins : evidence for independent roles of age and sex[J]. Diabetologia,2003,46(4) :459.

二级参考文献33

  • 1李光伟,Step.,L.检测人群胰岛素敏感性的一项新指数[J].中华内科杂志,1993,32(10):656-660. 被引量：2125
  • 2[1]Scherer PE,Williams S,Fogliano M,et al.A novel serum protein similar to Clq,produced exclusively in adipocytes.J Biol Chem,1995,270:26746-26749.
  • 3[2]Fruebis J,Tsao TS,Javorschi S,et al.Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice.ProcNatl Acad Sci USA,2001,98:2005-2010.
  • 4[3]Tomas E,Tsao TS,Saha AK,et al.Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain:acety1-CoA carboxylase inhibition and AMP-activated protein kinase activation.Proc Natl Acad Sci USA,2002,99:16309-16313.
  • 5[4]Yamauchi T,Kamon J,Mizokoshi Y,et al.Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMPactivated protein kinase.Nat Med,2002,8:1258-1259.
  • 6[5]Ouchi N,Kihara S,Arita Y,et al.Adipocyte derived plasma protein adiponectin,suppresses lipid accumulation and class A scavenger receptor expression in human monocyte derived macrophages.Circu-lating,2001,103:1057-1063.
  • 7[7]Poulter N.Coronary heart diaease is a mulfifactorial disease.Am J Hypertens,1999,12:S92-S95.
  • 8[8]Philip KG,Gregorio D,Lu T,et al.Adiponectin expression from human adipose tissue:relation to obesity,insulin resistance and tumour necrosis-αexpression.Diabetes,2003,52:1779-1785.
  • 9Arita Y, Kihara S, Ouchi N, et al. Paradoxic decrease of an adipose-specific protein, adiponectin, in obesily[J]. Biochem Biophys Res Commun,1999,257:79-83.
  • 10Hanley AJ, Connelly PW, Harris SB, et al. Adiponeclin in a native Canadian populalion experiencing rapid epidemiological Iransilion[J]. Diabetes Care,2003,26:3219-3225.

共引文献82

同被引文献39

  • 1薛建波,杨丽.脂联素与肝纤维化[J].医学综述,2007,13(2):116-118. 被引量：8
  • 2Tamura T, Furukawa Y, Taniguchi R, et al. Senm adiponectin level as an independent predictor of mortality in patients with congestive bear failure. Circ J,2007,71 ( 5 ) :623 - 630.
  • 3Shibata R, Izumiya Y, Sato K, et al. A diponectin Protects against the development of systolic dysfunction following myocardial infarctino. J MoI CeLL Cardio1,2007,42 ( 6 ) : 1065 - 1074.
  • 4Shibata R, Izumiya Y, Sato K, et al. Adiponectin protects against the development of systolic dysfunction folloming myocardial infarction. J MoI CeLL Cardiol,2007,42(6) :1065 - 1074.
  • 5Waki H,Yamauchi T,Kamon J,et al.Impaired multimerization of human adiponectin mutants associated with diabetes.Molecular structure and multimer formation of adiponectin[J].J Biol Chem,2003,278(41):40352- 40363.
  • 6Yamauchi T, Kamon J,Ito Y,et al.Cloning of adiponectin receptors that me- diate antidiabetic metabolic effects[J].Nature,2003,423(6941):762-769.
  • 7Henriksen PA,Newby DE.Therapeutic inhibition of tumour necrosis fac- tor alpha in patients with heart failure:cooling an inflamed heart [J]. Heart,2003,89(1):14-18.
  • 8Chen H,Montaqnani M,Funahashi T,et al.Adiponectin stimulates produc- tion of nitric oxide in vascular endothelial cells[J].J Biol Chem,2003,278 (45):45021-45026.
  • 9Tao L,Gao E,Jiao X,et al.Adiponectin cardioprotection after myocardial ischemia/reperfusion involves the reduction of oxidative/nitrative stress [J].Circulation,2007,115(11):1408-1416.
  • 10Singh I,Carey AL,Watson N,et al.Oxidative stress-induced insulin re- sistance in skeletal muscle ceils is ameliorated by gamma-tocopherol treatment[J].Eur J Nutr,2008,47(7):387-392.

引证文献4

二级引证文献17

心血管病学进展
2009年 第1期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部