Making brundlefly, one gene at a time
Making brundlefly, one gene at a time
摘要
Drosophila melanogaster has proved to be a remarkable organism for studying complex biological phenomenona. One of the great virtues ofD. melanogaster is its amenability to large scale genetic screens. Many types of genetic screen have been performed in D. melanogaster in the past with great success, to explore myriad biological processes such as tissue growth, differentiation, patterning, morphogenesis, and immunity. Different types of genetic screens employed include：
参考文献1
-
1Rong Xu,Kejing Deng,Yi Zhu,Yue Wu,Jing Ren,Min Wan,Shouyuan Zhao,Xiaohui Wu,Min Han,Yuan Zhuang,Tian Xu.A large-scale functional approach to uncover human genes and pathways in Drosophila[J].Cell Research,2008,18(11):1114-1127. 被引量：5
二级参考文献44
-
1Benson DA, Karsch-Mizrachi I, Lipman D J, Ostell J, Wheeler DL. GenBank. Nucleic Acids Res 2006; 34:D16-D20.
-
2Venter JC, Adams MD, Myers EW, et al. The sequence of the human genome. Science 2001; 291:1304-1351.
-
3Lander ES, Linton LM, Birren B, et al. Initial sequencing and analysis of the human genome. Nature 2001; 409:860-921.
-
4Collins FS, Green ED, Guttmacher AE, Guyer MS. A vision for the future of genomics research. Nature 2003; 422:835- 847.
-
5Adams MD, Celniker SE, Holt RA, et al. The genome sequence of Drosophila melanogaster. Science 2000; 287:2185- 2195.
-
6Phelps CB, Brand AH. Ectopic gene expression in Drosophila using GAL4 system. Methods 1998; 14: 367-379.
-
7Rφrth P. A modular misexpression screen in Drosophila detecting tissue-specific phenotypes. Proc Natl Acad Sci USA 1996; 93:12418-12422.
-
8Brand AH, Perrimon N. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 1993; 118:401-415.
-
9Crosby MA, Goodman JL, Strelets VB, Zhang P, Gelbart WM, FlyBase Consortium. FlyBase: genomes by the dozen. Nucleic Acids Res 2007; 35:D486-D491.
-
10Freeman M. Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye. Cell 1996; 87:651-660.
共引文献4
-
1LI HongYan,PAN LiXia,GOU KeMian.Depletion of ribosomal protein L8 impairs Drosophila development and is associated with apoptosis[J].Science China(Life Sciences),2010,53(9):1092-1097. 被引量：3
-
2李红艳,潘丽霞,苟克勉.敲除核糖体蛋白L8对果蝇发育的阻滞与细胞凋亡紧密相关[J].中国科学：生命科学,2010,40(8):724-730. 被引量：1
-
3罗中钦,金龙国,邱丽娟.大豆miR1511／1511＊共同切割GmRPL4a基因[J].科学通报,2012,57(20):1928-1935.
-
4LUO ZhongQin,JIN LongGuo,QIU LiJuan.MiR1511 co-regulates with miR1511* to cleave the GmRPL4a gene in soybean[J].Chinese Science Bulletin,2012,57(28):3804-3810.
-
1Acta Biochimica at Biophysica Sinica[J].生物化学与生物物理学报,2003,35(11).
-
2ZHANG Wen,XIE Huazhen,LI Qing,ZHANG Lu,LIU Ciquan.Splicing Signals in the Human Hemoglobin Genes at the Sequence and Folding Levels[J].Wuhan University Journal of Natural Sciences,2011,16(2):93-100.
-
3One Gene,Three Diseases:How Small Changes Cause Big Differences[J].Chinese Journal of Biomedical Engineering(English Edition),2014,23(2):65-65.
-
4Jodi A. Gullicksrud,Qiang Shan,Hai-Hui Xue.Tcf1 at the crossroads of CD4^＋ and CD8^＋ T cell identity[J].Frontiers in Biology,2017,12(2):83-93.
-
5李沐阳,翁曼丽,童克忠.Mechanism of regulating the expression of λN gene by ribosomal protein at translational level[J].Science China(Life Sciences),1998,41(1):29-36. 被引量：1
-
6亓希武,徐道华,于盱,房海灵,李维林,梁呈元.金银花肌动蛋白基因LjActin的克隆及在花发育过程中的表达分析[J].江西农业学报,2017,29(3):90-94. 被引量：6
-
7张帆,李瑞梅,袁帅,耿梦婷,姚远,刘姣,段瑞军,符少萍,胡新文,郭建春.木薯钙/CaM调控类受体激酶基因MeCRLK1的克隆及生物信息学分析[J].基因组学与应用生物学,2017,36(4):1581-1587. 被引量：2
-
8李赵志,严昌国,张立春,曹阳,金海国.吉林梅花鹿IGF-I基因启动子区单核苷酸多态性分析[J].安徽农业科学,2010,38(13):6729-6730. 被引量：5
