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肺动脉高压的遗传机制研究进展 被引量:3

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出处 《华西医学》 CAS 2009年第1期223-225,共3页 West China Medical Journal
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参考文献19

  • 1Zaiman A,Fijalkowska I, Hassoun PM, et al. One hundred years of research in the pathogenesis of pulmonary hypertension[J]. Respir Cell Mol Biol, 2005,33 (5) : 425-431.
  • 2Thomson JR, Machado RD, Pauciulo M, et al. Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR Ⅱ ,a receptor of the TGF-B family[J]. J Med Genet,2000,37(10) :741-745.
  • 3陆立鹤,荆志成,邹玉宝,张芊,惠汝太.骨形成蛋白Ⅱ型受体基因R491W突变导致家族性原发性肺动脉高压[J].中国循环杂志,2002,17(5):380-382. 被引量:6
  • 4Morse JH ,Deng Z,Knowles JA. Genetic aspects of pulmonary arterial hypertension[J]. Ann Med,2001,33(9):596-603.
  • 5Cool CD, Stewart JS, Werahera P, et al. Three-dimensional reconstruction of pulmonary arteries in plexiform pulmonary hypertension using cell-specific markers:evidence for a dynamic and heterogeneous process of pulmonary endothelial cell growth[J]. Am J Pathol, 1999, 155(2):411-419.
  • 6Trembath RC,Thomson JR,Machado RD,et al. Clinical and molecular genetic features of pulmonary hypertension in patients with hereditary hemorrhagic talangiectasia[J]. N Engl J Med,2001,345(5), 325-334.
  • 7Eddahibi S, Humbert M, Fadel E, et al. Serotonin transporter overexpression is responsible for pulmonary artery smooth muscle cell hyperplasia in primary pulmonary hypertension[J]. J Clin Invest,2001, 108(8) :1141-1150.
  • 8Eddahibi S, Hanoun N, Lanfumey L,et al. Attenuated hypoxic pulmonary hypertension in mice lacking the 5-hydroxytryptamine transporter gene[J]. J Clin Invest,2000,105(11) :1555-1562.
  • 9Long L,MacLean MR,Jeffery TK,et al. Serotonin increases susceptibility to pulmonary hypertension in BMPR 2-deficient mice[J]. Circ Res,2006,98(6):818-827.
  • 10Yuan JX, Rubin LJ. Pathogenesis of pulmonary arterial hypertension:the need for multiple hits[M]. Circulation, 2005,111(5): 534-538.

二级参考文献20

  • 1[1]Pietra GC,Edwards WD,Kay JM,et al.A qualitative and quantitative study of pulmonary blood vessels from 58 patients in the national heart,lung,and blood institute,primary pulmonary hypertension registry.J Circulation,1989,80:1198-1206.
  • 2[2]Tuder RM,Groves B,Badesch DB,et al.Exuberant endothelial cell growth and elements of inflammation are present in plexiform lessions of pulmonary hypertension.Am J Pathol,1994,144∶275-285.
  • 3[3]Cool CD,Stewart JS,Werahera P,et al.Three-dimensional reconstruction of pulmonary arteries in plexiform pulmonary hypertension using cell-specific marlcer:evidence for a dynamic and heterogeneous process of pulmonary endothelial cell growth.Am J Pathol,1999,155∶411-419.
  • 4[4]Thomson JR,Machado RD,Pauciulo MW,et al.Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-Ⅱ,a receptor of the TGF-β family.J Med Genet,2000,37∶741-745.
  • 5[5]Deng Z,Morse JH,Slager SL,et al.Familial primary pulmonary hypertension(Gene PPH)is caused by mutation in the bone morphogenetic protein recepter-Ⅱ(BMPR2)gene.Am J Hum Genet,2000,67∶737-744.
  • 6[6]Nichols WC,Koller DL,Slovis B,et al.Localization of the gene for familial primary pulmonary hypertension to chromosome 2q31-32.Nat Genet,1997,15∶277-280.
  • 7[7]Lane KB,Machado RD,Pauciulo MW,et al.Heterozygous germline mutations in BMPR2,encoding a TGF-beta receptor,cause familial primary pulmonary hypertension.Nat Genet,2000,26∶81-84.
  • 8[8]Morse JH,Knowles JA.Genetics of primary pulmonary hypertension.Progress in Pediatric Cardiology,2001,12∶271-278.
  • 9Nakagawa N,Osanai S,Ide H,et al.Severe pulmonary hypertension associated with primary Sjogren's syndrome.Intern Med,2003,42:1248-1252.
  • 10Koopmam WJ,Moreland LW,eds.Arthritis and allied conditions.15th ed.Philadelphia:Lippincott Williams & Wilkins,2004.1249-1680.

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