Kartagener综合征3例分析并文献复习

Kartagener syndrome： three cases report and literature review

目的供临床医师提高对Kartagener综合征早期诊断和治疗。方法通过3例病史、临床表现、影像学、彩超、心电图等检查明确诊断进行分析和文献复习。结果Kartagener综合征是一种少见的常染色体隐性遗传性疾病，症状为：副鼻窦炎一支气管扩张一内脏转位三联征，其临床表现为反复咳嗽、咯脓痰、咯血等肺部表现，同时伴副鼻窦炎。结论在内脏转位的患者中若出现支气管扩张症状及影像学表现．应想到Kartagener综合征的可能。

Objective To improve the early diagnosis and treatment of Kartagener syndrome. Methods The clinical presentation, radiography, ulfrasound cardiogram, electrocardiogram changes of 3 patients were studied,and the relatated literature was reviewed. Results Kartagener syndrome is a rare autosomal recessive genetic disease, recognized by the three symptoms of chronic sinusitis, bronchiectasis,situs inversus. The most common initial symptoms are cough, sputum and sinusitis. Conclusion If the patients with situs irversus have the clinical presentations and radiography of brouchiefasis,it should be thought of Katagener syndrome.