RNA干扰技术治疗呼吸道合胞病毒感染的研究进展
Progress of RNA interference technology in treatment of RSV infection
摘要
呼吸道合胞病毒(RSV)是婴幼儿呼吸道感染的主要病原体,大部分儿童感染后仅表现为上呼吸道感染,少部分可发展为毛细支气管炎,且RSV感染与支气管哮喘的发生发展密切相关。RNA干扰技术是细胞内天然的基因沉默与调节机制,已被广泛用于病毒感染的治疗研究。该文就近年对RSV基因结构和功能以及RNA干扰技术应用于防治RSV感染的研究进展进行综述,并讨论RNA干扰治疗RSV的可行性和应用展望。
出处
《国际儿科学杂志》
2009年第1期20-22,共3页
International Journal of Pediatrics
基金
2007年广东省科技厅科学事业费科技计划项目(2007B030704004)
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