摘要
目的观察丙泊酚复合雷米芬太尼、异氟醚复合雷米芬太尼两种醉方法用于老年人腹腔镜胆囊切除术维持期间血流动力学指标的变化。方法62例拟在气管插管全麻下择期行腹腔镜胆囊切除术的老年病人随机分为丙泊酚组和异氟醚组两组,每组31例。快速诱导后经口插入气管导管,麻醉维持丙泊酚组采用0.1mg·kg-1·min-1丙泊酚和1μg·kg-1·min-1雷米芬太尼静脉泵入,异氟醚组采用0.8%～1.5%异氟醚吸入和1μg·kg-1·min-1雷米芬太尼静脉泵入。于麻醉诱导后10min、手术开始后30、45、60min以及术毕30min记录平均动脉压(MAP)、中心静脉压(CVP)、心排血量(CO)、心脏指数(CI)等血流动力学指标值。结果临床麻醉剂量的丙泊酚复合雷米芬太尼、异氟醚复合雷米芬太尼对病人血流动力学指标的影响均较轻,两组间血流动力学指标的差异无统计学意义。结论两种麻醉方法对老年人腹腔镜胆囊切除术维持期间心血管功能的影响程度相似。
Objective To evaluate the effect of propofol/isoflurane, sevoflurane/remifentanil on cardiovascular system in the elderly patients undergoing lapsroscopic surgery. Methods Sixty - two ASA Ⅰ or Ⅱ patients undergoing elective laparoseopic cholecystectomy were randomly divided into two groups ： propofol group （ n = 31, group P） and isoflurane group（ n = 31, group Ⅰ）. After rapid induction all patients were intubated with a tube. Anesthesia was maintained with continuous infusion of propofol 0. 1 mg · kg^-1· min^-1 and isoflurane 1 μg· kg^-1· min^-1 in group P, 0.8% - 1.5% end - tidal concentration of sevoflurane and remifentanil μg· kg^-1· min^-1 in group I. Hemodynamic variables includiug cardiac output（ CO）, cardiac index（CI） were continuously measured through -out anesthesia. Resuits The hemodynamic status of all patients was little influenced by any one of two anesthesia techniques in P group or in S group at clinical dosages. Conclusions In ASA Ⅰ or Ⅱ elderly patients undergoing lapsroscopic surgery propofol affects CO, CI in a similar degree to sevoflurane.
出处
《医学信息（手术学分册）》
2008年第11期996-998,共3页
Medical Information Operations Sciences Fascicule
