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急性非等容量血液稀释联合控制性降压对腹部手术病人血液动力学及氧代谢的影响

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摘要 目的评价急性非等容量血液稀释(ANIH)的安全性及有效性。方法选择择期腹部手术患者40例,随机分为ANIH联合血液稀释和控制性降压(CH)组(A组)和单纯CH(C组),每组20例。观察两组输液量、输血量、血液动力学变化、Hct及氧代谢变化。结果A组MAP在T1明显高于T0及C组;在T2、T3两组均明显低于T0、T1和T4(P<0.05),但组间差异无显著性(P<0.05)。HRA组T1明显减慢,C组T2~T4明显快与T0、T1和A组(P<0.05)。A组CVP、CO、CI(ERO2)在T1~T3均明显高与T0及C组。SVR和DO2T1~T3则显著低于T0、T4及C组(P<0.05)。A组在T3、T4两组Hct均明显低于T0(P<0.05)。两组VO2及LAC在稀释前后无明显变化(P<0.05)。结论术前ANIH联合硝酸甘油CH可减少术中用血,且有助于腹部手术病人血液动力学的稳定,不影响机体氧化谢。
出处 《江西医药》 CAS 2008年第12期1382-1383,共2页 Jiangxi Medical Journal
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