类风湿关节炎患者的情感障碍

AFFECTIVE DISORDERS IN PATIENTS WITH RHEUMATOID ARTHRITIS

目的：了解类风湿关节炎（ＲＡ）患者的情感障碍，以及情感障碍与个性、病情及治疗的关系。方法：采用Ｚｕｎｇ焦虑自评量表（ＳＡＳ）、抑郁自评量表（ＳＤＳ）和艾森克个性问卷（成人）（ＥＰＱ），调查了８０例ＲＡ患者与５０例正常人，通过多重线性回归和Ｌｏｇｉｓｔｉｃ回归分析探讨ＳＡＳ、ＳＤＳ得分与个性、ＲＡ病情指标及治疗的关系。结果：ＳＡＳ、ＳＤＳ得分与患ＲＡ及不良个性有关；ＲＡ抑郁与Ｅ分、功能障碍及甲氨喋呤治疗有关。结论：ＲＡ患者存在焦虑、抑郁情感障碍，ＲＡ抑郁的发生可能与个性内倾、功能障碍及长期使用甲氨喋呤有关。

Objective:To know affective disorder in rheumatoid arthritis(RA) and the association of depression with personality, clinical character and therapy. Method:investigated 80 RA patients and 50 normal controls with selfreported anxiety scale (SAS),selfreported depression scale (SDS)and Eysenck personality questionnaire (EPQ), analysed the relationship between depression and Eysenck personality, clinical indicators or therapy using liner regression and logistic regression. Results:SAS and SDS score were relivant with RA and personality; RA depression was relevant with E score, disability and MTX therapy.Conclusion: RA patients might have anxiety and depression, the development of depression in RA patients was associated with introversion, disability or MTX therapy.