糖尿病心功能异常早期诊断的临床探讨

Clinical study on the early diagnosis of abnormal heart function in diabetes mellitus patient

目的探讨糖尿病人心功能异常的早期诊断。方法使用非侵入性心脏血流动力学监测仪心阻抗图对30例正常人和87例无临床心脏病症状和体征的糖尿病人检测，并进行比较。结果57例患者存在心功能异常：心脏每搏输出量（SV）及每分输出量（CO）减少，血管顺应性（AC）下降，总外周阻力（TPE）增高（P＜0．001）；左室射血时间（LVET）缩短，收缩时间间期（STI）延长（P＜0．05）。直线相关分析显示：年龄（Ag）、平均动脉压（MAP）及体重指数（WI）与AC、SV、LVET分别呈负相关，与TPR及STI正相关；病程（DD）与CO、SV、LVET负相关，与STI正相关（P＜0.01）。结论非侵入性血流动力学测定对糖尿病人心功能减退可提供早期诊断，控制血糖、体重及血压对延缓心脏病变的发生发展具有重要意义。

Objective To search the early diagnosti method of abnormal diabetic heart function. Methods wemeasured thirty health subjects and 87 patients of diabetes mellitus (DM) without evidence of heart disease onclinical by noninvasive hen1odynamic mortor. Results 57 DM patients suffered from abnormal heart function.The SV.CO and AC was lesser, the TPR was higher then normal (P < 0.001 ); LVET shorter, STI longer thanthat in health subjects. The results of linear relative analyse showed that Ag、MAP and WI was nagtively re1ated toAC、 Co、 SV、 LVET, positively to TPR and STI; DD was nagtively related to CO、 SVLVET. Positively to STI.Conclusions Noninvasive hemodynamic mortor rheocardiogram is a good method for early diagnosis in DMabnormal heart function. Maintaining normal body weight and blood pressure and blood glucose is very importantfor preventing development from diabetic heart disease