麻黄与杏仁混合汤剂红外光谱分析

Infrared Spectrum Analysis of Admixture Decoction of Herba Ephedrae with Semen Armeniacae Amarum

测试了单味药麻黄、杏仁及麻黄+杏仁混合汤剂的红外光谱。经分析:在麻黄+杏仁汤剂中保留了麻黄、杏仁单味药物汤剂中的某些吸收峰,见麻黄+杏仁光谱1402和1076 cm-1处等;麻黄、杏仁光谱中的某些吸收峰并未在麻黄+杏仁光谱中出现,见麻黄+杏仁光谱1394和682 cm-1处等;在麻黄+杏仁汤剂光谱中,出现了新的吸收峰,见麻黄+杏仁光谱688和1187 cm-1处等。同时,因吸收峰位置的改变,说明各基团在麻黄、杏仁、麻黄+杏仁汤剂中所处的化学环境不同,汤剂中生化物质的结构发生了变化,或麻黄+杏仁汤剂中可能新生成了麻黄、杏仁单味药物汤剂中所没有的化学成分。麻黄+杏仁汤剂所包含的药物成分并非是单味麻黄、杏仁汤剂所含药物成分的简单相加。

The infrared spectra of decoction of herba ephedra and semen armeniacae amarum and the mixed decoction of herba ephedra ＋ semen armeniacae amarum were tested.The change in the the mixed decoction was discussed to study the relationship between herba ephedra and semen armeniacae amarum after decoction.The results showed that some absorption peaks of herba ephedra and semen armeniacae amarum were retained in the mixed decoction of herba ephedra ＋ semen armeniacae amarum,such as 1 402 and 1 076 cm^-1,but some absorption peaks that never appear in the two ingredient spectra increased such as 1 394 and 682 cm- 1.New absorption peaks were generated in the mixed decoction of herba ephedra ＋ semen armeniacae amarum,such as 688 and 1 187 cm- 1.It can be showed that there were differences in the chemistry environment of the various chemical groups in the three decoctions introduced above,with the variation in absorption peak position,and the biochemical structure of the material changed,possibly with some new chemical compositions created.Medical ingredients in the mixed decoction of herba ephedra ＋ semen armeniacae amarum were not simply the addition of herba ephedra and semen armeniacae amarum.based on studies of infrared spectrum of decoction,and the new notion of prescription spectroscopy was proposed.