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干扰素治疗慢性丙型肝炎近远期疗效

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摘要 目的:应用重组干扰素治疗慢性丙型肝炎近期与远期疗效观察研究。方法:3×106IU,ih,1次/2d×3个月为1疗程,接受2-4个疗程干扰素治疗的慢性丙型肝炎患者20例,治疗结束后随访观察1-3年。结果:根据干扰素疗效评价标准,第2个疗程治疗结束时,分别有45,0%(9/20),40.0%(8/20)和15.0%(3/20)的患者表现为完全应答,部分应答和无应答。完全应答者有3例分别在第2疗程结束后的6个月、9个月的间隙期内复发。有6例患者接受3-4个疗程治疗。在2-4个疗程治疗结束后随访1-3年,6例(30.0%)患者表现为持续完全应答,11例(55.0%)患者为部分应答,3例(15.0%)患者无应答。结论:慢性丙型肝炎患者干扰素治疗的早期疗效较好,但完全应答者的复发率较高。
出处 《广东医学》 CAS CSCD 1998年第5期389-390,共2页 Guangdong Medical Journal
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参考文献4

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