90名强制戒毒人员丙肝感染状况检测分析

An analysis of HCV infection in 90 people who have to stop taking harmful drugs

目的:通过对电白县某戒毒所共92名强制戒毒人员进行艾滋病的初筛检测后,将余下90名抗-H IV阴性的进行抗-HCV、HBsAg及肝功能谷丙转氨酶(ALT)等项目的检测,并随机抽取50名同年龄组社会健康人员进行ALT项目检测分析比较,从而探讨丙肝感染、吸毒等对强制戒毒人员肝功能的损害状况。方法:静脉采血5 m l,待凝固后离心取血清,根据《中国临床检验操作规程》(第3版)以及试剂说明书,采用酶联免疫吸附试验(ELISA法)进行抗-HCV、HBsAg检测[1],按速率法进行肝功能(ALT)检测,并对检测结果进行统计学处理及评估。结果:90名强制戒毒人员中抗-HCV和HBsAg均呈阳性的共15人,单纯抗-HCV阳性的55人,单纯HBsAg阳性的1人,抗-HCV和HBsAg均呈阴性的19人;55名单纯抗-HCV阳性者其ALT均值为60.3 U/L,15名抗-HCV及HBsAg均呈阳性者其ALT均值为29.1 U/L,19名抗-HCV和HBsAg均呈阴性者其ALT均值为27.1 U/L,50名社会健康人员其ALT均值为19.9 U/L,将均值60.3 U/L分别和均值29.1、27.1和19.9 U/L作t′检验,其差异均有特别显著统计学意义。结论:丙肝感染在强制戒毒人员中比率很高,达77.8%(70/90),且丙肝感染对强制戒毒人员的肝功能损害也是明显的。

Objoctive：In order to know how their liver function is after they take drugs and their livers are infected.One stop-taking-harmful-drug office in Dianbai has 90 people who are against HIV negative examined on against HCV,HBsAg and ALT after the 92 people who are to stop taking drugs have the AIDS examined.The office also has 50 healthy people of the same age from computer examined on ALT.Methods：Take 5 ml blood from the vein and after it becomes solid,take the serum out of the blood by turning round.According to China Clinic Examine Operation Rules（Edition 3） and reagent instructions,they use ELLSA to examine against HCV,HBsAg and Spead-rate to have ALT examination.Then,they have the results dealt with and evaluated according to the statistics.Results：From the 90 people,15 of them have against HCV ane HBsAg positive,55 of them have against HCV positive and 1 has HBsAg positive.Only 19 have against HCV and HBsAg negative.The ALT of the 55 people who have against HCV positive is on average of 60.3 U/L,the ALT of the 15 people who have against HCV and HBsAg posilive is on average of 29.1 U/L,the ALT of the 19 people who have against HCV and HBsAg negative is on average of 27.1 U/L,and the ALT of the healthy people from outside is on average of 19.9 U/L.After we have t′ examination on the 60.3 U/L with the 29.1,27.1 and 19.9 U/L,and compare them,we find the difference is very significant in statistics.Conclusion：The rate of the liver infection in the people who are to stop taking harmful drugs is very high up to 77.8%（70/90） and it′s also obvious that the liver infection does harm to the liver function of them.