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硒防癌抗癌机制的研究进展 被引量:13

Anti-cancer mochanism of selenium:recent progress
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摘要 研究表明,硒是一种具有防癌、抗癌作用的微量元素,适量补硒能使癌症的发病率和病死率下降。硒的防癌、抗癌机制是多方面的,主要包括抗氧化损伤、调控基因表达促进癌细胞凋亡、调节细胞周期促进癌细胞凋亡、稳定DNA的结构抵御组织癌变、提高机体免疫功能抵御组织癌变、硒介入某些化学致癌剂的代谢等。但也应指出,硒的生物学效应具有双重性,一方面缺硒会引起异常反应,另一方面高浓度的硒又可引起中毒反应。硒防癌、抗癌机制的阐明将可能为未来肿瘤治疗开辟一条新的途径。
出处 《中国肿瘤生物治疗杂志》 CAS CSCD 2008年第6期598-600,共3页 Chinese Journal of Cancer Biotherapy
基金 河北省科学技术研究与发展资助项目(No042761265)~~
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