有和无重叠症状的肠易激综合征患者生活质量及精神心理状况比较研究

The Quality of Life and Mental-Psychological Stautus in Irritable Bowel Syndrome with or without Overlapping Symptoms:A Comparative Study

目的调查有和无重叠症状的肠易激综合征(IBS)患者的生活质量、精神心理状况,分析有重叠症状IBS患者生活质量特点,探讨影响其生活质量的主要因素及重叠症状产生的可能原因。方法对2007年10月至2008年4月在我院消化科门诊就诊的、符合罗马Ⅲ诊断标准的76例IBS患者建立健康档案,采用消化道症状调查表、汉化版简明健康调查量表(SF-36)、焦虑自评量表(SAS)和抑郁自评量表(SDS)进行问卷调查。根据问卷调查结果将其分为有重叠症状组(食管、胃、十二指肠和肛门直肠症状)和无重叠症状组,分析比较两组患者生活质量和精神心理状况,并对结果进行统计学分析。结果有重叠症状组IBS患者生活质量较无重叠症状组降低,合并焦虑抑郁状态的比例高于无重叠症状组(P<0.05)。结论伴随重叠症状的IBS患者生活质量受到影响,不良精神心理因素可能是其生活质量主要影响因素及重叠症状产生的原因。

Objective To investingate the quality of life（QOL） and mental stautus in irritable bowel syndrome（IB5） patients with or without overlapping symptoms（ OS）, and to analysis the features of QOL in patients with OS to find out the its possible affecting factors and the possible cause of OS. Methods According to diagnostic criteria of Rome Ⅲ ,76 cases of IBS patiens were divided into two groups using the gastrointestinal symptom rating scale （GSRS） ：with OS （esophageal, gastroduodenal or antrectal symptoms） or without OS （ only intestinal symptoms）. The two groups of patients were investingated by using the Chinese version of short from 36 health survey questionnaire （SF-36） , self-rating anxiety scale （SAD） , self-rating depression scale （SDS） . All the scales were compared and analyzed. Results The scale of QOL deereasead more significantly in OS group than that in without OS group,and more patients with OS were in anxiety-depression staus（ P 〈0, 05）. Conclusion IBS with OS has a significant impact on QOL of patients,which is related to the abnormal psychological status. Abnormal psychological factors may be involved in the mechanisms underlying OS.