Tei指数在评价海员慢性阻塞性肺病患者右心室功能中的应用

Evaluation of Tei index on right ventricular function in patients with chronic obstructive pulmonary diseases

目的探讨Tei指数在评价海员慢性阻塞性肺病患者右心室功能中的作用。方法在我院2006年至2007年住院的海员患者及健康体检者中选取慢性阻塞性肺病患者38例，正常对照组98例，行超声心动图检查测量有心Tei指数、肺动脉收缩压等。结果（1）与正常对照组相比，慢性阻塞性肺病患者右心室等容舒张时间（IRT）及等容收缩时间（ICT）明显延长，射血时间（ET）明显缩短，右室Tei指数明显升高（P〈0．01）；（2）肺动脉高压组间比较显示肺动脉高压的程度对右室Tei指数有一定影响，组间比较差异有统计学意义（P〈0．01）。（3）右心大小组间比较显示右室扩大的Tei指数增大，但组间比较差异无统计学意义（P〉0．05）。结论（1）Tei指数是评价慢阻肺患者右心室收缩舒张功能简便、敏感、综合的多普勒超声新指标；（2）右心室Tei指数受压力负荷增加影响大，受容量负荷增加影响小，其右室功能受损程度与肺动脉收缩压升高有一定相关性。

Objective To investigate the evaluation of Tei index on right ventricular function in patients with chronic obstructive pulmonary diseases （ COPD ）. Methods Tirty-eight cases with COPD and ninty-eight healthy people were selected as COPD groups and normal control group. Tei index of right ventricular on eehocardiography and pulmonary arterial systolic pressure were observed. Results （ 1 ） There were significant differeces of isovolumic relaxation time （IRT） and isovolumetfic contraction time （ICT） , ejection time （ET） and Tel index of right ventrieular between healthy group and normal control group（ P 〈 0. 01 ）. （2） In comparison of COPD group, it showed that tel index was changed by the degree of PAH（ P 〈 0. 01 ）. There was significant differece in COPD group comparison （ P 〈 0. 01 ）. （ 3 ） Tei index in right ventricular enlargement increased by PAH while decreased by volume load. Conclusions （ 1 ） Tei index is one of convenient, sensitive and general Doppler ultrasound index which can evaluate function of ventrieular contraction and diastolic in patients with COPD. （2） Tei index in fight ventricular enlargement was influeed by pressure load and volume load, respectively. There was a correlation between the degree of right ventricular function damage and increasing of pulmonary arterial systolic pressure.