肝炎后肝硬化腹水病人的营养评价与血浆游离氨基酸分析

Assessment of Nutritional Status and Determination of Free Amino Acid in Patients with Post Hepatitis Cirrhosis Ascites

对１８例肝炎后肝硬化腹水（ＨＬＣＡ）病人进行了药物和膳食治疗前后的营养状态评价和血浆游离氨基酸（ＰＦＡＡ）测定。结果：治疗后三头肌皮褶厚度（ＴＳＦ）、上臂肌围（ＭＡＭＣ）、部分必需氨基酸（ＥＡＡ）和半必需氨基酸（ＣＥＡＡ）等均较治疗前显著升高（Ｐ＜０．０５，Ｐ＜０．０１），支链氨基酸与芳香氨基酸比值（ＢＣＡＡ／ＡＡＡ）和ＴＳＦ之间存在显著正相关。结果表明ＨＬＣＡ时营养不良更趋恶化以及营养膳食治疗的重要性；证实ＰＦＡＡ的含量水平能够反映病人的营养状态。

he nutritional status and plasma free amino acid (PFAA) of 18 patients with post hepatitis cirrhosis ascites (HLCA) were assessed before and after the treatment with medication and diet. The result showed that triceps skinfold fat (TSF),mid arm muscle circumference (MAMC),the level of some essential amino acids (EAA) and conditioned essential amino acids (CEAA) were singificantaly increased after the treatment (P<0.01,P<0.05).There was a good correlation between the ratio of branchedchain amino acid (BCAA)to aromatic amino acid (AAA) and TSF. It is suggested that ascites may worsen the nutritional status in post hepatitis cirrhosis and the complex treatment with diet is extremely important. It is confirmed that the level of PFAA can reflect the nutritional status of the patients. 