脑卒中后继发癫痫45例临床分析

Clinical Analysis of 45 Patients with Epilepsy after Stroke

目的探讨脑卒中后继发癫痫的临床特点、发病机制及治疗。方法对495例脑卒中患者临床资料进行回顾性分析。结果495例脑卒中继发癫痫45例,占9.09%,且男性高于女性。发作类型以部分性发作最多。皮质发生率明显高于皮质下,首次发作多在脑卒中3周内。结论当脑卒中累及大脑皮层或脑血液循环障碍导致神经元异常放电时易继发癫痫。

Objective To explore clinical features,pathogenesis and treatment for epilepsy after stroke. Methods 495 patients with epilepsy caused by stroke were retrospectively analysed. Results Out of 495 apoplexy stroke patients,45 with epilepsy accounted for 9.09%, the male was higher than female. The outbreak type was mostly partial outbreak. The cerebral cortex formation rate is obviously higher than those under the cerebral cortex. The first time stroke usually happened within 3 weeks of apoplexy. Conclusion When the apoplexy implicates the cerebral cortex or the disturbance of brain blood circulation causes abnormal neuron discharges, secondary epilepsy is liable to happen.