摘要
目的观察阿托伐他汀对急性心肌梗死的临床效果。方法将我院86例AMI患者随机分为治疗组及对照组,对照组给予常规治疗,治疗组加服阿托伐他汀。结果经过治疗,两组患者的TC、TG、LDL、ET-1和NO均有显著改善,与治疗前比较差异有统计学意义(P<0.05);治疗组改善更加明显,优于对照组,差异有统计学意义(P<0.05)。治疗1年后心血管事件比较,治疗组的梗死后心绞痛、再发性心肌梗死、心力衰竭例数显著少于对照组,差异有统计学意义(P<0.05)。结论早期应用阿托伐他汀治疗AMI能明显减轻炎症反应,具有调脂作用,不良反应小、安全性和耐受性好,值得临床推广和应用。
Objective To observe atorvastatin treatment of acute myocardial infarction. Methods 86 cases of AMI patients were randomly divided into treatment and control groups,control group given conventional treatment,treatment group taking atorvastatin. Results After treatment,Two groups of patients with TC,TG,LDL,ET-1 and NO were significantly improved,there was a significant difference than before treatment （P 〈 0.05）; The treatment group improved significantly more, better than the control group,there was a significant difference（P〈0.05）. Conclusion Early atorvastatin treatment of AMI can significantly reduce inflammation,can adjust blood lipids, and small adverse reactions,safety and tolerability of good,worthy of promotion.
出处
《中国现代医生》
2009年第2期12-13,共2页
China Modern Doctor
关键词
早期应用
阿托伐他汀
急性心肌梗死
效果
Early application
Atorvastatin
Acute myocardial infarction
Results
