早期肠内营养支持对急性胰腺炎患者康复效果的影响

Evaluating Recovery Effect and Feasibility of Enteral Nutrition in Patients with Severe Acute Pancreatitis

目的评价早期肠内营养治疗重症急性胰腺炎的临床效果和安全性。方法48例急性重症胰腺炎患者随机分为观察组(n=24)和对照组(n=24),其中观察组采用早期肠内营养治疗,对照组采用传统的一般治疗方法,对两组患者的预后情况、炎症反应情况、肠内营养不良反应等情况进行比较。结果观察组和对照组ICU停留时间、住院时间、第10天APACHEⅡ评分及第10天CT评分均无显著性差异(P>0.05);两组治疗前后C反应蛋白、白细胞计数均明显下降(P<0.05);而且两组血小板计数也均有所升高(P>0.05)。结论尽早对重症急性胰腺炎患者行早期肠内营养支持治疗是安全有效的措施。

Objective To evaluate the recovery effects and feasibility of enteral nutrition（EN）in patients with severe acute pancreatitis （SAP）. Methods 48 SAP patients were divided randomly into two groups. Research group was treated with EN,and control group was treated with separate solutions. Then the days that patients were treated in ICU department or stay in hospital,APACHE Ⅱ scores after 10 days of treatment and C reactive protein or WBC were analyzed before and after treatment. Results Days being hospitalized or being treated in ICU, APACHE Ⅱ scores after 10 days of treatment between research and control groups were not significantly different（P〉0.05）;while,in both groups,the C reactive protein and WBC count after 10 days treatment were declined significantly（P 〈 0.05） compared with before treatment. Conclusion Compared with separate solutions treatment ways, EN is effective and feasibility for severe acute pancreatitis patients.