深圳市宝安区地中海贫血及G-6-PD缺乏的调查

The Inquisition of Mediterranean Anaemia and G-6-P-D Lack in the Bao'an District of Shenzhen City

目的通过对地中海贫血及G-6-PD缺乏症的筛查,预防和控制重症地中海贫血的发生,降低G-6-PD缺乏的发病率。方法地中海贫血筛查:地贫一管定量筛选法。血红蛋白电泳:法国sebia公司HYDRASYS全自动电泳系统进行血红蛋白电泳;G-6-P-D筛查:G-6-P-D/6PGD定量比值法。结果宝安区α地贫发生率为5.72%,β地贫发生率为2.25%,G-6-P-D缺乏症发生率为2.22%。结论进行地中海贫血及G-6-PD缺乏症的筛查可有效地控制重症地中海贫血的发生,降低G-6-PD缺乏的发病率。

Objective Through check of Mediterranean anaemia and G-6-P-D lack,prevent and control occurrence of Mediterranean anaemia, and lower the outbreak rate of G-6-PD lack. Methods Mediterranean anaemia screening： ＂a tube method＂; Hemoglobin electrophoresis. The sebia electrophoresis technique was, used for Hemoglobin electrophoresis. G-6-PD sieving check：G-6-P-D/6PGD fixed amount specific value method. Results The Baoan District α-tbalassemia occurrence rate was 5.72%; The β-thalassemia occurrence rate was 2.25%; The G-6-P-D lack occurrence rate was 2.22%. Conclusion Mediterranean anaemia and G-6-PD lack screening, can control the occurrence of Mediterranean anaemia availably, and lower the G-6-PD lack outbreak rate.