阿托品抢救急性有机磷农药中毒208例分析及对患者预后的影响

Effects of artopine on prognosis of patients with acute organophosphorus pesticide poisoning:208 cases report

目的:观察阿托品抢救急性有机磷农药中毒208例及对患者预后的影响.方法:对我院2005-01/2007-12急性有机磷农药中毒的患者208例进行回顾性分析,Ⅰ组为服毒后3h内达到阿托品化103例,Ⅱ组为服毒3h后达到阿托品化105例,比较两种并发症和病死率的发生率.结果:与Ⅰ组相比,Ⅱ组病死率高(18.1%vs7.8%,P<0.05),并发症发生率高.结论:阿托品抢救急性有机磷农药中毒时阿托品化达到的时间越早,患者的治疗效果和预后越好,病死率发生越少.

AIM： To study the effects of artopine on the prognosis of 208 patients with acute organopbosphorus pesticide poisoning （ AOPP ）. METHODS ： The acute organophosphorus pesticide poisoning patients, admitted from January 2005 to December 2007, were retrospectively analyzed. The 208 patients were divided into two groups according to the periods of reaching artopinization. Group Ⅰ reached artopinization within 3 hours （n = 103 ） and group Ⅱ reached atropinization beyond 3 hours （n = 105）. Complications and mortality between the two groups were compared. RESULTS： The complications and mortality in group Ⅰ were lower than those in group Ⅱ. CONCLUSION： The time of artopinization is associated with the prognosis of AOPP. The earlier the artopinization, the better the prognosis and the lower the mortality rate.