Molecular mechanisms of metastasis in prostate cancer

前列腺癌症(PCa ) 优先地转移到轴的骨骼的骨头髓基质。这项活动是 PCa 病态和死亡的主要原因。PCa 转移的准确机制当前是未知的，尽管可观的进步在在这进程决定关键播放器被取得了。在这评论，我们在场驾驶 PCa 转移到骨头的分子的过程的当前的理解。

Prostate cancer （PCa） preferentially metastasizes to the bone marrow stroma of the axial skeleton. This activity is the principal cause of PCa morbidity and mortality. The exact mechanism of PCa metastasis is currently unknown, although considerable progress has been made in determining the key players in this process. In this review, we present the current understanding of the molecular processes driving PCa metastasis to the bone.