美托洛尔舌下含服治疗老年急症高血压(24例临床报告)

Treatment of acute hypertension in aged person by sucking Metoprolol under tongne

本文旨在评估舌下含服美托洛尔对老年高血压急症的降压效果。方法：２４例老年急症高血压患者，于舌下含服美托洛尔５０ｍｇ前及含服后５、１０、３０、６０及１２０分钟，动态监测血压及心率，并比较用药前及用药后各时间段降压效果。结果：（１）治疗前、治疗后５、１０分钟，均有非常显著差异（Ｐ＜００１，Ｐ＜００５），１０分钟血压降至安全水平，３０分钟完全降至正常，且降压效应持续至２小时。（２）无明显副作用。结论：舌下含服美托洛尔对老年急症高血压患者，是一种速效，稳效，无明显副作用，且方法简便的急症降压方法。

Aim Evaluating the hypotensive efficacies of sublingually administing metoprolol in elder hypertensive emergency patients.Method Selecting 24 consecutive elder hypertensive emergency patients,prestudy and after administing metoprolol 50mg Sublingually,mornitoring BP and HR at 5、10、30、60 and 120 minutes and comparing the hypotensive efficacies between prestudy and after taking medication at warious time intervals.Results (1) the change between prior and after administing medication show significantly difference (P<0 01,P<0 05 respectively),within 10 minutes,lowering to safe level and stablely maintaining hypotensive efficacy 2 hours. (2)No intolerant side effects.Conclusion The sublingually administing metoprolol for treating elder hypertensive emergency patients is a rapid 、stable offective、convenient、noobvious side effective therapeutic method.