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深圳地区消化不良患者调查研究

Survey on dypepsia in Shengzhen area
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摘要 目的:探讨提高对消化不良患者的临床诊断和鉴别能力。方法:对我市多家医院就诊的927例消化不良患者进行调查并随访,最后按国际标准诊断。结果:56.4%的患者为功能性消化不良(FD),36.7%为良性器质性消化不良(OD),6.9%为恶性消化不良。当有明显报警症状(AS)时,良性OD和恶性消化不良分别升至49.4%和28.7%,显著高于无AS的患者(35.1%和3.9%,P<0.01)。随年龄增加,FD的比例逐渐降低,而恶性肿瘤则相反,后者在60~75岁患者中达29.3%,40岁以下14例,占1.5%,其中1例(7%)无AS。大量服用非类固醇抗炎药(NSAID)患者中器质性疾病占68.8%,显著高于未服用者(45.5%)。结论:40岁以下患者已有恶性肿瘤可能,应警惕。有AS,大量服用NSAID均提示OD,应及时进行相关临床检查及随访。 Objective:To improve the capability identifying the causes of dyspepsia. Methods:Standardized questiowaires were used to investigate 927 dyspeptic outpatients among four hospitals in Shengzhen area.All of the patients were followed up for 4-24 weeks, and finally diagnosed according to consistent criteria.Results :The frequency rate of functional dyspepsia (FD) was 56.4%,benign organic causes were present in 36.7% and malignant diseases accounted for the remaining 6.9%. In the patients with marked alarm symptoms, the proportion of benign organic causes and malignant diseases rose to 49.4% and 28.7% respectively, significantly higher than that without alarm symptoms (35.1% and 3.9% respectively,P〈0.01). The rate of FD declined with the increase of age. The opposite tendency appeared within those with malignant causes. The rate of malignant causes in the 60-75 years group reached 29.3%. The number of patients younger than 40 years old with malignant causes was 14 (1.4%), of whom 1(7.0%) had no alarm symptoms. The rate of organic dyspepsia was 68.8% in the patients taken over-dose non-steroidal anti-inflammatory drugs (NSAIDs),the figure significandy higher than that in low dose or non-NSAIDs users. Conelusion:h should be noted that malignancy might be present in the patients below 45 years old. Alarm symptom and NSAIDs use are two risk factors that can predict the organic dyspepsia.
出处 《现代医药卫生》 2009年第4期511-513,共3页 Journal of Modern Medicine & Health
关键词 消化不良 疾病 诊断 Dyspepsia Disease Diagnosis
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参考文献5

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