摘要
以大鼠小肠纵行肌条的收缩活动为指标,观察了枳实对大鼠离体小肠平滑肌收缩活动的影响.结果表明:枳实明显减小大鼠小肠纵行肌条的收缩波平均振幅,但不影响小肠纵行肌张力及收缩波频率.六烃季胺、心得安、消炎痛、LNNA不影响枳实对小肠纵行肌条的抑制作用,而酚妥拉明可部分拮抗枳实的抑制作用.由此可见,枳实明显抑制大鼠离体小肠纵行肌的收缩活动,该作用可能部分经由肾上腺素能α受体介导.
The effect of Zhishi on the contraction of small intestinal longitudinal strips was studied in rats.Zhishi significantly decreased the mean contractile amplitude of longitudinal muscle(LM) of small intestine in rats,phentolamine inhibited the effect of Zhishi partly,but hexamethonium,propranolol,indomethacin and L NNA did not.It had no obvious effect on the tension and the contractile frequency of LM of small intestine.It was concluded that Zhishi significantly inhibited the contraction of small intestinal longitudinal muscle,which may be mediated by α receptor.
出处
《西北师范大学学报(自然科学版)》
CAS
1998年第2期69-72,共4页
Journal of Northwest Normal University(Natural Science)
关键词
枳实
小肠
离子平滑肌
平滑肌
运动生理
Zhishiratsmall intestinal longitudinal musclePhentolamine