成都市阻塞性睡眠呼吸暂停低通气综合征患者高血压患病率的研究及相关因素分析

The study on the association between obstructive sleep apnean-hypopnea syndrome and hypertension in Chengdu and research related factors

目的研究成都市阻塞性睡眠呼吸暂停低通气综合征患者高血压患病率及分析睡眠呼吸暂停低通气指数(AHI)、体重指数(BMI)、颈围/身高的比值等因素与高血压的相关性。方法通过睡眠呼吸障碍高血压发病情况问卷调查表对350例阻塞睡眠呼吸暂停低通气综合征患者进行问卷调查,所有患者均在睡眠实验室进行至少7 h的夜间睡眠呼吸监测,监测患者的血压、血氧饱和度、AHI、体重指数、颈围/身高的比值等。结果在纳入的350例OSAHS患者中,高血压的患病率为27.14%,男性明显高于女性。AHI指数的高低与OSAHS患者高血压的患病率呈正相关。阻塞睡眠呼吸暂停综合征高血压量表的问卷对OSAHS合并高血压的患者诊断成功率高、可靠性均较高。结论350例OSAHS患者中,高血压的患病率为27.14%,年龄、AHI、BMI与高血压有统计学相关性,回归方程式为:Y=-6.718+0.818X1+1.068X2+0.433X3,(1为年龄,2为体重,3为AHI),对回归模型以及其系数的显著性检验说明模型显著有效。

Objectives We study the association between obstructive sleep apnea-hypopnea syndrome and hypertension in Chengdu and research related factors just as apnea hypopnea index,body mass index,c-cireumstan/beight rafio,et al.Methods 350 patients with OSAHS were investigated with questionnaire, and all patients had been monitored at least for 7 hours in the lab. The indexes include apnea hypopnea index, body mass index, e-circumstan/height ratio, et al. Results In the 350 patients with OSAHS, the incidence of hypertension is 27.14 % ,and the male is more than the female.The level of AHI index contributes to the incidence of patients with OSAHS and hypertension. The sleep-apnea-hypertensive questionnaire was a facticity and reliable tool.Conclusion In the 350 patients with OSAHS, the incidence of hypertension is 27.14 %. There are statistical correlation between age,AHI,BMI and hypertension. Regression equation： Y = - 6.718 ＋ 0.818 X1 ＋ 1.068 ）（2 ＋ 0.433 ）（3（ 1 for age, body weight for 2, 3 for AHI） ,Through the signifi- canoe test of rite regression model and the coefficient, we prove the model significantly efficient.