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75例白血病的免疫分型分析 被引量:1

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摘要 目的探讨白血病免疫分型及其临床意义。方法选用CD13、CD14、CD33、CD2、CD5、CD7、CD10、CD19、CD20、CD22、CD9、CD64、CD34、HLA-DR等14种胞膜抗体,采用流式细胞仪、CD45-ssc双参数设门检测75例白血病患者免疫分型情况。结果75例各种类型白血病中,ALL23例,5例T-ALL均表达T系抗原,其中3例交叉表达CD13,3例表达CD22;18例B-ALL均表达B系抗原,其中交叉表达CD13有14例,CD33有2例,CD2有2例。髓系白血病52例,按FAB分型,M02例,M15例,M25例,M38例,M4/M526例,CML6例,交叉表达CD7有11例,CD2有4例,CD194例,CD22有10例,75例各种类型白血病中CD34阳性50例,阳性率为67%。HLA-DR53例,阳性率为67%,M3中为阴性表达。结论流式细胞仪三色免疫荧光直接标记法进行白血病免疫分型能确诊一些特殊类型的白血病,对于急性白血病的诊断治疗和预后判断均有很大的帮助。
作者 王述文
出处 《海南医学》 CAS 2009年第2期84-86,共3页 Hainan Medical Journal
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