钯催化1-(2-溴苯基)-2-丙醇的内酯化

Palladium-Catalyzed Lactonization of 1- (2-Bromophenyl ) -2-Propanol

报道钯催化下，1－（2-溴苯基）－2-丙醇与一氧化碳的内酯化反应．探讨温度、催化剂、时间和溶剂对反应的影响，优选出最佳实验条件，使3-甲基-3，4-二氢-1H-苯并[C]吡喃-1-酮的收率达到95．1％．

The lactonization of 1-(2-bromophenyl )-2-propanol with carbon nonoxide was studied.The effects of reaction conditions were discussed. Under optimum conditions, 3-methyl-3,4-dihydro-1H-benzo[C] pyran-1-one was synthesized in a 95. 1 % yield.