我院2006—2007年抗肿瘤药物用药分析

Analysis of Anticancer Drugs Used in Our Hospital During Period 2006—2007

目的了解抗肿瘤药物的应用情况。方法采用限定日剂量法、销售金额排序法和用药频度(DDDs)分析法进行统计、分析。结果医院抗肿瘤药物用药金额略有上升;其他抗肿瘤药及辅助药和抗肿瘤植物药占有相当大的市场份额;多西他赛销售金额连续2年位居榜首,奥沙利铂由2006年销售榜的第3位跃居至2007年的第2位;连续2年DDDs最高的为三苯氧胺。结论抗肿瘤植物药、辅助治疗药、抗代谢药和抗肿瘤抗生素系抗肿瘤的主要用药,其销售金额与DDDs在用药管理中具有同等重要的地位;建议临床医师多选择疗效确切、不良反应少、价格便宜的国产抗肿瘤药物,为国家医保基金和患者减少负担。

Objective To analyze the situation of antineoplastic drugs used in our hospital. Methods According to the original data of Kingstar Winning Corporation THIS computer management system in our hospital, we used the daily dosage restrictions, the amount of sales sort of medication and defined daily dose （DDDs） method for statistical analysis. Results The amount of anticancer medication in our hospital increased slightly; and other anti-tumor drugs and adjuvant therapy drugs and anti-tumor botanic drugs occupied a certain market share; the sales of docetaxel placed the top in two consecutive years. Oxaliplatin leapt from the third place in 2006 sales list to the second place in 2007; in two consecutive years the highest DDDs was Tamoxifen. Conclusion The main anti-tumor drugs such as anti-tumor botanical drugs, adjuvant therapy drugs, anti- metabolism drugs and anti- tumor antibiotics, the amounts of their sales are as important as the frequency of medication in the medication management. Doctors are recommended to use the domestic anti- tumor drugs with best efficacy, light side effect and cheap price according to the guiding principles of anti- tumor clinical studies for lowering the treatment costs of National Health Insurance and patients.