广东瑶族人群HBsAg阳性与ABO血型的相关性研究

Relations between HBsAg-positive and ABO Blood Groups of Chinese Yao Nationality in Guangdong

目的了解广东瑶族人群HBsAg阳性与ABO血型的相关性。方法采用ELISA法及微量板法分别检测1559例瑶族人群血液HBsAg与ABO血型,并对HBsAg阳性者的ABO血型分布及性别分布进行分析。结果共检出HB-sAg阳性299例,总阳性率为19.18%,其中男性为19.70%,女性为18.70%,男女阳性率差异无统计学意义(χ2=0.25,P>0.05)。不同性别HBsAg阳性者的血型分布特点为:男性:A>O>AB>B,女性:AB>O>A>B,不同性别分布差异无统计学意义(χ2=8.51,P>0.05)。HBsAg阳性者中A2亚型阳性率为66.67%,A2亚型全部为女性。结论广东瑶族人群HBsAg阳性率高于全国平均水平,HBsAg阳性者的ABO血型分布无性别差异。

Objective To study the relations between HBsAg-positive and ABO blood groups. Methods HBsAg- positive and ABO blood groups were detected respectively by ELISA and micro-plate in 1 559 Yao population. The distributions of HBsAg-positive in ABO blood groups as well as sex groups were analysed by Chi-square （χ^2） test. Results There were 299 HBsAg-positive patients among the total 1 559 cases. The total HBsAg positive rate was 19.18%. Male positive rate was 19.70% while that of female was 18.70%. There was no statistically significant difference between different sex groups. The distribution of HBsAg-positive people in ABO blood group was A〉O〉AB〉B in male,and AB〉O〉A〉B in female. There was no significant difference of ABO blood group distribution on sex（χ^2=8.51,P〉0.05）. HBsAg positive rate of A2 subgroup accounted for 66.67% ,and all of the patients were female. Conclusion The HBsAg positive rate of Yao nationality in Guangdong was higher than average level of the whole country. There was no statistically significant difference of HBsAg-positive population＇s blood types in different sex groups.