深圳市龙岗区病毒性肝炎患者血清学分型监测分析

Results of serotyping of viral hepatiti patients in Longgang District,Shenzhen City

目的分析深圳市龙岗区病毒性肝炎患者血清学分型监测结果。方法采集静脉血5ml分离血清,-20℃保存。每2个月用冷藏车或者冰瓶专人送至市疾病预防控制中心急性传染病防治科检验室。用酶联免疫吸附法(ELISA)检测抗-HAV-IgM、HBsAg、抗-HBs、抗-HBc、抗HBcIgM、抗-HCV、抗HEVIgM等。结果抗-HAV-IgM总阳性检出率为1.55%,其中仅2002年为5.19%,其余年均为0。HBsAg总阳性检出率为34.44%,HBsAg+抗-HBc总阳性检出率为34.13%,HBsAg+抗HBcIgM总阳性检出率为5.56%,抗-HBcIgM总阳性检出率为13.21%。抗-HEVIgM总阳性检出率为8.17%,波动在1.90%～38.46%之间。未分型即总未检出率39.96%,波动在16.67%～60.00%之间。结论乙、丙型型肝炎仍然是目前重点防治的传染病。戊型肝炎的防治已经刻不容缓。

Objective To analyze the results of serotyping of viral hepatitis patients in Longgang District, Shenzhen City. Methods Veinous blood samples of 5ml were collected and stored at -20℃ and tested in Shenzhen Municipal Center for Diseae Control and Prevention. The levels of anti-HAV-IgM, HBsAg, anti-HBs, anti-HBc, anti-HBclg,anti-HCVand anti-HEVIgM were determined by ELISA and analyzed. Results The positive rate of anti-HAV-IgM was 1.55%, the total positive rate of HBsAg was 34.44%, the total positive rate of HBsAg＋anti-HBe was 34.13%, whiloe that of HBsAg ＋anti- HBclgM and HBsAg ＋anti-HBelgM were 5.56% and 13.21%. The total positive rate of anti-HEVIgM was 8.17% . Conclusion Hepatitis B and C are currently the target infectious diseases in this district and the control of hepatitis E should also be carried out as quickly as possible.