超声雾化吸入辅助治疗菌阳肺结核疗效观察

The study of the effect of the treatment of smear positive pulmonary tuberculosis with steam inhalations

目的：探讨超声雾化吸入治疗菌阳肺结核的临床治疗价值。方法：将60例菌阳肺结核患者（包含初治与复治）随机分为治疗组和对照组，初治患者采用2HRZE/6HR，复治患者采用3ADTVEZ/15DTVE，治疗组患者前3个月加用异烟肼及链霉素超声雾化吸入，每天2次，然后比较两组在临床症状改善率、痰菌阴转率、病灶显效率等方面的差异。结果：雾化治疗结束时两组患者的症状改善率、痰菌阴转率、病灶显效率之间存在显著性差异（P〈0.0 5）。结论：超声雾化吸入辅助全身化疗治疗可加快菌阳肺结核患者症状改善、痰菌阴转及病灶吸收，且没有明显毒副作用。该方法经济、方便、有效、便于推广。

Objective：To evaluate the efficacy of the treatment of smear positive pulmonary tuberculosis with steam inhalations.Methods：60 cases of smear positive pulmonary tuberculosis were randomly divided into the treatment group and the control group（including the primaries and the retreated）.The primaries were treated with 2HRZE/6HR,while the retreated patients were treated with 3ADTVEZ/15DTVE,the treatment group accepted steam inhalations,which involved adding isoniazid and streptomycin,twice a day in the first three months,then Comparisons were made between the two groups in the sputum clinical symptoms improvement rate,tubercle bacillus conversion rate ,radiographic improvement rate and other.Results：By the end of 3 months ,there were all significant difference in the sputum clinical symptoms improvement rate,tubercle bacillus conversion rate and radiographic improvement rate between the two groups（P〈0.05）.Conclusion：Steam inhalations-assisted chemotherapy treatment could speed up the bacteria-positive tuberculosis patients to improve symptoms,sputum conversion and lesion absorption, and no apparent side effects.It was economic,convenient,worthwhile and easy to promote.