白蛋白降低对脑出血患者预后的影响

Influence on the prognosis of cerebral hemorrhage patients with low serum albumin

目的探讨血清白蛋白降低对脑出血患者预后的影响。方法用病例一对照研究的方法分析比较89例血清白蛋白（serum albumin，SAL）降低（SAL〈40g／L）脑出血患者及257例血清白蛋白正常（SAL≥40g／L）脑出血患者日常活动能力（Barthel指数）、病死率及并发症的发生率。结果入院时2组患者Barthel指数比较差异无统计学意义（P〉0．05）。1个月及3个月低血清白蛋白组患者Barthd指数与正常血清白蛋白组患者比较差异有统计学意义（P〈0．05）。血清白蛋白降低与脑出血患者的病死率（OR：3．01．95% CI 1．69～5．26）及肺部感染率（OR=3．17，95％ CI 1．85～5．42）密切相关。结论血清白蛋白降低与脑出血患者日常活动能力障碍、病死率及肺部感染率密切相关。营养支持治疗是脑出血综合治疗的重要方法。

Objective To explore the influence on the prognosis of cerebral hemorrhage patients with low serum albumin. Methods A case-control analysis was used. Daily action ability（Barthel index）, the death rate and the occurrence rate of complication were compared in 89 cerebral hemorrhage patients with low serum albumin （SAL〈40g/L） and 257 cerebral hemorrhage patients with normal serum albumin （SAL≥40g/L）. Results When being hospitalized,low serum albumin group patients compared with normal serum albumin group patients, Barthel index had no significant difference （P〉0.05）. After 1 month and 3 months,Barthel index had significant difference （P〈0.05）between two groups. Low serum albumin was closely related to the death rate （OR=3.01,95% CI 1.69-5.26） and lung infection rate （OR=3.17,95%CI 1.85-5.42） of cerebral hemorrhage patients. Conclusion Low serum albumin is closely related to the obstacle of daily action ability,the death rate and lung infection rate in cerebral hemorrhage patiens. Nutrition support treatment is good for the comprehensive treatment of cerebral hemorrhage.