生血宁治疗缺铁性贫血的临床研究

Study on Treatment of Iron Deficiency Anemia with Shengxuening

目的观察生血宁治疗缺铁性贫血的临床疗效。方法60例缺铁性贫血患者口服生血宁2片，3次，d，治疗28d。观察治疗后第1、2、3、4周外周血红系指标红细胞（RBC）计数、血红蛋白（Hb）值、红细胞压积（HCT）、平均红细胞体积（MCV）、平均红细胞血红蛋白量（MCH）、平均红细胞血红蛋白浓度（MHCH）、以及网织红细胞（Ret）计数的变化。结果1周后Ret上升，2周后Hb上升，4周后Hb、MCV、MCH、MHCH基本正常。同时发现生血宁的胃肠道副作用明显低于其他铁剂。结论生血宁治疗缺铁性贫血有效且胃肠道副作用小。

Objective To observe the therapeutic effect of Shengxuenin（SXN） in treating iron deficiency anemia（IDA）. Methods 60 cases with IDA from January 2007 to June 2008 were treated with SXN, 2 pellets Tid per os for 30 days. The value of erythrocyte count （RBC）, haematoglobin （ Hb ）, hematocrit （HCT）, mean corpuscular volume （MCV）, mean corpuscular haematoglobin （MCH）, mean corpuscular-hemoglobin concentration （MHCH）, Reticulocyte （Ret） was observed at the first week, the second week, the third week and the fourth week of the treatment. Results Reticulocyte count started to increase at the 1st week and haematoglobin count started to increase at the 2nd week. Haematoglobin, mean corpuscular volume, mean corpuscular haematoglobin and mean corpuscular-hemoglobin concentration returned to normal at the 4th week. The gastrointestinal side effects of this therapy were fewer than treated with other chalybeate medicines. Conclusion SXN was effective in the treatment of IDA and had little gastrointestinal side effects.