HBV X 基因及前C区突变对临床的影响
被引量:1
摘要
HBVX基因及前C区突变对临床的影响王志刚毕平安王兆丰王君耀作者单位:314000浙江嘉兴二院(王志刚毕平安王兆丰)浙江医科大学附属邵逸夫医院(王君耀)HBV-DNA核苷酸负链的长度为3.2kb,其基因共有6个开放读码框架(ORF),主要为S、C、P...
出处
《临床肝胆病杂志》
CAS
北大核心
1998年第2期76-78,共3页
Journal of Clinical Hepatology
参考文献10
-
1Fukuda R,Xuan-Thanh N,Isbimura N,et al.X gene and precore region mutations in the hepatitis B virus genome in persons positive for antibody to hepatitis B e antigen J Infect Dis.1995.172:1191.
-
2Hong-yan H,Mri-Hwei C,Chin-Yun L,et al.Precore mutant of hepatitis B virus in childhood fulminant hepatitis B,J Infect Dis.1995;171:776.
-
3Hasegawa K,Huang J.Rogers SA.et al.Enhanced replication of a hepatitis B virus mutant associated with an epidemic of fulminant hepatitis.J Virol.1994.68:1651.
-
4Feitelson MA.Duan LX.Guo J,et al.X region deletion variant of hepatitis B virus in surface antigennegative intections and Non-A Non-B hepatitis.J Infect Dis.1995;172:713.
-
5Nakatake H,Chisaka O,Yamamoto S,et al.Effect of X protein on transaction of hepatitis B virus promoters and on viral replication.J Virol.1993.195:305.
-
6Ritter S,Whitten T,Quets A,et al.An internal domain of the hepatitis B virus x antigen is necessary for transactivating activity.J Virol.1991;183:825.
-
7Arii M,Takada S,Koike K.Identification of three essential region of hepatitis B Virus x protein for trans-activation function.Oncogene,1992.7:397.
-
8Zhou DX.Taraboulos A,Ou JH,et al.Activation of class I msjor histocompatibility complax gene expression by hepatitis B Virus J Virol.1990.64:4025.
-
9Zhu M,London WT,Duan LX.The valu of hepatitis B X antigen as a prognostic marker in the development of hepatocellular carcinoma.Int J Cancer Res.1993.55:571.
-
10Xu J,Brown D,Harrison T,et al.Absence of hepatitis B Virus precore mutants in patients with chronic hepatitis B responding to interferon-alpha.Hepatology.1992.15:1002.
同被引文献5
-
1张宜俊,孔祥平,郑国池,陈光明,杨富强.促肝细胞生长素治疗慢性病毒性肝炎1668例疗效观察[J].临床肝胆病杂志,1995,11(3):137-140. 被引量:51
-
2盛国光.慢性乙型肝炎中医病因病机的探讨[J].中西医结合肝病杂志,1997,7(2):126-127. 被引量:37
-
3徐陈槐,刘克洲.乙型肝炎病毒S区基因变异与临床[J].肝脏,1999,4(1):56-59. 被引量:1
-
4徐克成,危北海,姚希贤,张万岱.慢性乙型肝炎当代中西医结合治疗[J].世界华人消化杂志,1999,7(11):970-974. 被引量:30
-
5张宜俊,陈光明,孔祥平,郑国池,杨富强,胡肇椿.肝细胞生长素的研制及临床应用[J].临床肝胆病杂志,1991,7(1):15-19. 被引量:123
-
1无症状慢性乙肝患者ALT可自发升高[J].现代医院,2009,9(4):95-95.
-
2胡德昌,李晓芳,熊思东,屠红,刘厚钰,闻玉梅.慢性乙型肝炎患者乙型肝炎病毒前C区基因突变与干扰素的关系[J].中华内科杂志,1995,34(4):229-231. 被引量:18
-
3李复领,陈双峰.110例乙型肝炎患者外周血单个核细胞中HBV-DNA X基因片段检测分析[J].山东医药,2003,43(17):26-26.
-
4田小平,何浩明,徐凤英,朱崇尧.肝硬变患者内分泌激素与HBVX基因相关性的初步探讨[J].放射免疫学杂志,1998,11(6):342-343.
-
5夏呈森.新生儿、婴儿心力衰竭的病因和诊断[J].小儿急救医学,1994,1(2):51-53. 被引量:1
-
6杨华文,朱燕,姚亚超,李亚红,李楠,曹东林,张智,胡亮杉.HBV前C区G1896A和G1899A促进e抗原血清学转换[J].实用医学杂志,2017,33(6):990-993. 被引量:4
-
7朱晓岚,潘小平.慢性乙型肝炎患者基因型以及其病毒载量前C区突变的研究[J].浙江临床医学,2006,8(8):850-851.
-
8方丽娟,任玲君,丁利胜.乙型肝炎病毒基因型与核心启动子及前C区突变关系研究[J].中国卫生检验杂志,2010,20(11):2850-2851. 被引量:1
-
9张梅菊,马小军,张津怀,甄梦妮.王志刚主任医师从肝脾论治甲状腺功能减退症经验[J].中医研究,2016,29(5):37-39. 被引量:5
-
10刘华瑞.乙型肝炎病毒基因组前C区突变的研究现状[J].广东医学院学报,1995,13(2):119-123.