牛骨移植及牙种植体植入的实验研究

Experimental study of cattle bone grafting in combination with implant insertion

目的探讨牛骨块在牙种植领域应用的可能性。方法将２０块牛骨外置移植于兔胫骨干骺端，同时植入牙种植体固定骨块。术后按计划给动物注射三种荧光素，并通过组织学和组织测量学方法评价新骨形成。结果荧光素标记的新骨逐渐替代移植骨的松质骨和部分皮质骨，实验结束时新骨已达牙种植体肩台平面。实验８４天，４个上位螺纹平面的骨面积明显高于２１天的骨面积。平均矿物沉积率为１．９０μｍ／ｄ～２．７５μｍ／ｄ。结论牛骨外置移植结合螺钉型牙种植体植入可增加受区骨量。

Objective To study the effect of cattle bone grafting in combination with implant insertion. Methods Twenty cattle bone blocks were onlayed on the rabbit tibial metaphysis, which were fixed by dental implants. Triple fluorochromes were sequentially given to animals following the operation. New bone formation was histologically and histomorphometrically evaluated. Results The fluorochrome labelled new bone gradually replaced almost all the spongy bone and the partial cortical bone of the graft at the end of the experiment. There was a significant higher percentage of bone area at the first four thread levels at 84 days than at 21 days. The average mineral apposition rates ranged from 1.90μm/d to 2.75 μm/d. Conclusion The onlay cattle bone grafting in conjunction with screw type dental implants can be used to increase the volume of the recipient bone.