原因不明发热89例临床分析

Clinical analysis on 89 cases of fever of unknown origin

目的探讨原因不明发热(FUO)的病因和临床特点。方法回顾性地总结分析2005年10月至2008年5月北京中日友好医院住院成人患者,符合FUO诊断标准者共89例。结果最终明确诊断者共80例,确诊率89.9%。病因:感染性疾病41例,占46.1%;风湿性疾病15例,占16.9%;肿瘤性疾病18例,占20.2%,其中血液系统肿瘤17例;其他疾病6例,占6.7%;未明确诊断9例,占10.1%。结论感染性疾病是FUO的主要病因,风湿性疾病和肿瘤性疾病是另两种主要病因。血液系统肿瘤是肿瘤性发热的主要病因。详尽的病史采集有助于诊断的确立。

Objective To investigate the causes and features of fever of unknown origin （FUO）. Methods This study enrolled 89 patients who fullfilled the criteria of FUO and were admitted in China-Japan Friendship hospital from October 2005 to May 2008. Results The final diagnosis were made in 80 cases（89. 9% ）. Etiologies of FUO were as follows：infections ,41 cases （ 46. 1% ） ; rheumatic disease, 15 eases （ 16.9% ） ; neoplasm, 18 cases （ 20. 2% ） （ hematological malignancy, 17 cases） , miscellaneous diseases 6 cases （ 6. 7 % ）, unknown etiology, 9 cases （ 10. 1% ） ： Conclusion Infection is the main cause of FUO ;rheumatic disease and neoplasm are also important causes of FUO. Hematological malignancy is the most common neoplasm related to FUO. Detailed history contributes greatly to FUO diagnosis.