龙岗区2001-2005年病毒性肝炎血清流行病学监测

Serum epidemiological surveillance of viral hepatitis in 2001-2005

目的研究一般人群血清病毒性肝炎免疫水平。方法在市级病毒性肝炎血清流行病学监测点内分别于2001、2003、2005年对一般人群免疫水平进行血清流行病学监测,用酶联免疫吸附法(ELISA)检测抗-HAV-IgG、HBsAg、抗-HBs、抗-HBc、抗-HCV等。结果抗-HAV-IgG总阳性检出率为82.38%,HBsAg总阳性检出率(2.79%),抗-HBs总阳性检出率(57.04%),抗-HBc总阳性检出率(46.94%),抗-HCV总阳性检出率(0.08%)。结论一般人群甲型肝炎抗体较高(82.38%),表明有关控制甲型肝炎的干预措施切实有效。乙型肝炎病毒感染总阳性率虽然较高(57.97%～62.22%),但仍提示乙型肝炎防治措施的重点应加强对10～20岁年龄组的疫苗接种。抗-HCV总阳性检出率(0.08%),近几年波动不大。

Objective To study on the immunity levels of serum viral hepatitis among general population. Methods To have a serum epidemiological surveillance for the immunity levels among the general population in the monitoring stations of the city in 2001,2003 and 2005. We used enzyme-linked immunosorbent assay （ELISA） to detect anti-HAV-IgG, HBsAg, anti-HBS, anti-HBc, anti-HCV, and so on. Results The total positive rate of anti-HAV-IgG was 82. 38%, the total positive rate of HBsAg was 2. 79%, the total positive rate of anti-HBS was 57.04%, the total positive rate of anti-HBc was 46. 94%, the total positive rate of anti-HCV was 0. 08%. Conclusion In general population,HAV antibody rate（82. 38% ）was at higher level and it is demonstrated effective to have these interventions for controlling diseases. Although the total infection positive rate of hepatitis B virus is higher than the others（57. 97% -62. 33% ） ,we should focus on the 10 to 20 ages group for strengthening vaccination on preventing and controlling hepatitis B. The total positive rate of anti-HCV is 0. 08% ,less volatility in recent years.