摘要
目的 了解阜外心血管病医院医院感染主要病原菌及耐药性,为临床合理使用抗菌药物提供依据。方法对2006—2007年医院分离的病原菌采用法国生物梅里埃公司VITEK32全自动微生物鉴定分析仪进行鉴定和药敏试验,用WHONET5.4软件进行统计分析。结果分离的病原菌中,以革兰阴性杆菌为主,对头孢他啶、头孢吡肟、阿米仁星、头孢哌酮/舒巴坦、哌拉西林/他唑巴坦敏感率较高,可达50.9%~94.7%;除铜绿假单胞菌外,对亚胺培南和美罗培南敏感率高,敏感率为98.7%~100.0%;革兰阳性球菌中,粪肠球菌对青霉素,高水平庆大霉素敏感率较高,敏感率分别为84.5%和94.5%;屎肠球菌对其敏感率低,敏感率分别为4.5%和11.9%;葡萄球菌属中以耐甲氧西林凝固酶阴性葡萄球菌为主,其对常用抗菌药物敏感率低;未出现万古霉素和替考拉宁耐药的葡萄球菌属和肠球菌属。结论了解医院感染病原菌的分布及耐药性,对临床合理使用抗菌药物,预防与控制医院感染发挥有效作用。
OBJECTIVE To investigate the pathogens and their drug-resistance in Fuwai Cardiovascular Hospital and provide antibiotics use suggestion for clinical treatment. METHODS The pathogens were identified by VITED 32 and analyzed by WHONET 5. 4 RESULTS The pathogens mainly consisted of Gram-negative bacilli, which were highly sensitive to imipenem and meropenem except Pseudomonas aeruginosa ; E. faecalis was much more sensitive to penicillin and gentamicin than E. faecium. Most coagulase-negative Staphylococcus (CNS) were resistant to oxacillin and showed low susceptibility rates to most antibiotics. No Gram-positive cooci were found to be resistant to vancomycin and teicoplanin. CONCLUSIONS To investigate the pathogens and their drug resistance is very important to prevent and control nosocomical infections.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2009年第2期228-230,共3页
Chinese Journal of Nosocomiology
关键词
医院感染
病原菌
耐药性
Nosocomical infection
Pathogen
Drug-resistance