急性缺血性脑血管病急性期治疗的思考被引量：1

下载PDF

导出

摘要急性缺血性脑血管病是由于局部脑血流突然阻塞而引起，应在寻找血管病变基础上尽快酌情选择溶栓、抗凝、抗血小板聚集、血管内治疗及手术治疗。现就急性期治疗的常见问题进行讨论。

作者李金

机构地区北京医院神经内科

出处《中华老年心脑血管病杂志》 CAS 北大核心 2009年第1期1-3,共3页 Chinese Journal of Geriatric Heart,Brain and Vessel Diseases

关键词脑缺血抗凝药支架

参考文献8

1Caplan LR. Caplan's stroke:a clinical approach, 3rd ed,Boston : Butterworth Heinemann, 2000.
2Arenillas JF. Metabolic syndrome linked with resistance to thrombolysis in stroke patients. Neurology, 2008, 71: 190- 195.
3Mattle HP, Arnold M,Georgiadis D, et al. Comparison of in traarterial and intravenous thrombolysls for ischemic stroke with hyperdense middle cerebral artery sign. Stroke, 2008,39:379-383.
4Rubiera M, Ribo M, Delgado MR, et al. Tandem internal carot id artery/middle cerebral artery occlusion:An independent pre dictor otpoor outcome after systemic thrombolysis. Stroke 2006,37:2301 2305.
5Prabhakaran S, Chong J Y, Sacco RL. Impact of abnormal diffusion-weighted imaging results on short-term outcome following transient ischemic attack. Arch Neurol,2007,64:1105 1109.
6Coutts SB, Hill MD, Campos CR, et al. Recurrent events in transient isehemic attack and minor stroke. Stroke, 2008,39: 2461-2466.
7Paciaroni M, Agnelli G, Corea F, et al. Early hemorrhagic transformation of brain infarction: rate, predictive factors, and influence on clinical outcome results of a prospective multicenter study. Stroke, 2008,39 : 2249-2256.
8Rosell A, Cuadrado E, Ortega AA, et al. MMP 9-positive neutrophil infiltration is associated to blood-brain barrier breakdown and basal lamina type IV collagen degradation during hemorrhagic transformation after human ischemic stroke. Stroke,2008,39 : 1121-1126.

1Nagano H, Suzuki T, Hayashi M, et al. Effects of a human urinary kininogenase(SK-827) on cerebral microcirculation after glass bead-induced cerebral embolism in rabbits. In Vivo, 1992,6:497-502.
2Campbell DJ. The kallikrein-kinin system in human. Clin Exp Pharmacol Physiol,2001,28:1060-1065.
3Bhoola KD, Figueroa CD, Worthy K. Bioregulation of kinins: kallikreins, kininogens, and kininases. Pharmacol Rev, 1992, 44:1-80.
4Groger M, Lebesgue D,Pruneau D, et al. Release of bradykinin and expression of kinin B2 receptors in the brain: role for cell death and brain edema formation after focal cerebral ischemia in mice. J Cereb Blood Flow Metab, 2005,25:978-989.
5Wagner S, Kalb P, Lukosava M, et al. Activation of the tissue kallikrein-kinin system in stroke. J Neurol Sci, 2002,202: 75- 76.
6Xia CF, Yin H, Borlongan CV, et al. Kallikrein gene transfer protects against ischemic stroke by promoting glial cell migration and inhibiting apoptosis. Hypertension,2004,43:452-459.
7Xia CF,Yin H,Yao YY,et al. Kallikrein protects against ischemic stroke by inhibiting apoptosis and inflammation and promoting angiogenesis and neurogenesis. Hum Gene Ther, 2006, 17:206-219.
8Ling L, Hou Q, Xing S, et al. Exogenous kallikrein enhances neurogenesis and angiogenesis in the subventricular zone and the peri-infarction region and improves neurological function after focal cortical infarction in hypertensive rats. Brain Res, 2008,1206 : 89-97.

中华老年心脑血管病杂志

2009年第1期

内容加载中请稍等...