不对称1,3,2-二氧磷杂环己烷非对映选择性合成及其生物活性

Diastereoselective Synthesis of Asymmetrical 1,3,2-dioxaphosphorins and Their Biological Activity

不对称１，３，２－二氧磷杂环己烷非对映选择性合成及其生物活性邵瑞链＊杨敏华成俊然（南开大学元素有机化学研究所，元素有机化学国家重点实验室天津３０００７１）关键词二氧磷杂环，立体有择合成，顺反异构体，生物活性１９９７－０６－０４收稿，１９９７－１２－０...

Diastereomers of 2 oxo 2 substituted phenoxy 4 phenyl 5,5 dimethyl 1,3,2 dioxaphosphorin were synthesized. The synthetic methods, solvents and salts appeared to exhibit significant influences on the cis/trans ratio of the products. The isomerization between cis and trans cyclic phosphates was investigated. The preliminary bioassay indicated that some isomers have herbicidal and plant growth activity.