无需待测化合物标准样品便可测定校正因子

Determination of Correction Factor Without Standard of Determined Compound

根据色谱峰面积、校正因子和待测组分含量的关系，应用Ｌｅｖｅｎｂｅｒｇ－Ｍａｒｑｕａｒｄｔ方法对气相色谱分析数据进行最优化计算，可在缺乏待测组分标准样品的条件下测定相应的校正因子。分别测定了甲苯－氯苯、二乙氧基甲烷－乙酸乙酯和二乙氧基甲烷－乙醇－水等３个体系中各组分的相对校正因子。结果表明：化合物校正因子的测定值与相应文献值的相对偏差小于３％。根据实验结果进一步讨论了方法的适用范围以及进行测定所需样品的数目。

A new method of determining correction factor without standard of compounds to be determined is proposed. Two initial mixtures, which contain compounds to be determined, were mixed in different proportions. The mixed samples were analyzed by gas chromotagraphy. Based on the relationship of contents to the peak areas and correction factors, the correction factors were calculated by using optimization with Levenberg Marquardt method. In order to verify the present method, toluene chlorobenzene, diethoxymethane ethanol water and diethoxymethane ethyl acetate were analyzed separately. Experimental results show that relative deviations of the correction factors determined by the present method from those reported in literatures were less than 3%. The determined correction factors are suitable for quantitative analysis. As the present method is applied, it is suggested that the number of the compounds in the mixture should not be more than 3. When the number of parameters equals 2, the number of samples necessary should be in the range from 10 to 12. When the number equals 3, it should be in the range from 12 to 14. In addition, the difference of content of the same component in the initial mixtures must be great enough, i.e., more than 20%.