螺旋霉素从水溶液中结晶成核动力学

THE NUCLEATION KINETICS OF SPIRAMYCINS

通过测量在不同的加热速率下的最大过热温度得到了螺旋霉素在水溶液中结晶成核的动力学，初级成核速率ｍＮ，ｐ＝７．０８９ｅｘｐ－１７．９９８×１０３１２９８．１５－１Ｔ［］ｅｘｐ－０．１１９ｌｎ２ｓ二次成核速率ｍＮ，ｓ＝０．３４１ｅｘｐ－３．５０８×１０３１２９８．１５－１Ｔ［］（ｃ－ｃｓ）１．３９２并用光散射方法测定估计出初级晶核的大小约为０．０５μｍ。

The nucleation kinetics of Spiramycins in aqueous solution has been obtained by measuring the maximum overheated temperature under different heating rates. The rate of the primary nucleation is N,p=7.089exp-17.998×10~31298.15-1T·exp-0.119ln2sand the rate of the secondary nucleation is N,s=0.341exp-3.508×10~31298.15-1T·(c-cs)1.392The particle size of the primary nucleation has been determined to be 0.05μm by Mic light scattering theory.