血清白蛋白水平对急性期脑血管意外患者运动功能恢复的影响

Effects of serum albumin level on motor functional outcome of the patients with acute cerebral vascular accident

目的：探讨血清白蛋白（ＳＡＬ）对急性期脑血管意外患者运动功能恢复的影响。方法：采用单盲前瞻性研究方法，将病情严重程度相同的４０例患者按ＳＡＬ分为高白蛋白组（ＳＡＬ≥４０ｇ／ｌ）和低白蛋白组（ＳＡＬ＜４０ｇ／ｌ），分析比较两组患者在急性期运动功能恢复情况。结果：ＡＨ组的合并症发生率显著低于低白蛋白组（Ｐ＜０．０１）；而高白蛋白组治疗后的ＭＡＳ积分及积分之差、ＭＢＩ积分之差均显著性高于低白蛋白组。结论：ＳＡＬ能够影响急性期脑血管病患者肢体运动功能的恢复。应对脑血管病患者的营养状况给予足够的重视。

Objective:To observe the relationships of serum albumin level (SAL) with motor functional recovery in acute cerebrovascular accident (CVA) patients. Method:A unilateral blinded and prospective study was adopted. We divided the 40 “middle-band' patients into two groups according to the SAL:higher serum albumin level group(AH,SAL≥40g/l);lower serum albumin level group(AL,SAL<40g/l).Result:There was a 9.52% complication rate for AH group and a 52.63% for AL group ( P <0.01), but the improvement of motor assessment scale (MAS) scores (20.52±8.98) and modified barthel index (MBI) scores (26.00±16.98) in AH group were both significantly higher than that of AL group (10.89±6.15,15.33±9.47), ( P <0 01, P <0 005 separately).Conclusion:SAL can affect acute CVA functional outcome. So we should pay more attention to the acute CVA patients′ nutrition and recommended that multidimentional nutritional support programs be included as part of the course of therapy. Author′s address Dept. Rehabilitation ,Union Hospital, Tongji Medical University, Wuhan, 430022