不同年龄组的角膜厚度及角膜曲率的变化规律

Changing rule of corneal thickness and corneal curvature in different age groups

目的:通过测定不同年龄人群的角膜厚度和曲率,了解随年龄增加角膜厚度和曲率的变化规律,探讨角膜厚度、曲率变化规律对于眼科临床治疗的指导意义。方法:连续收集2006-01/2007-09黄石爱尔眼科医院与黄石市疾控中心合作开展的社区普查临床资料,每个患者测量其中央角膜厚度、曲率及轴向,排除角膜溃疡、角膜白斑、圆锥角膜、角膜外伤等角膜疾病患者。将患者分为5组,A组5～10岁805例(1610眼),B组11～17岁535例(1060眼),C组18～40岁994例(1987眼),D组41～59岁723例(1445眼),E组60～80岁695例(1388眼),共3752例(7490眼)。采用SPSS11.5forWindows软件进行统计分析。结果:E组角膜厚度与其他4组比较差异有统计学意义,A,B,C,D,E组互相比较循规散光、逆规散光发生几率差异均有统计学意义(P<0.05)。结论:老年人角膜厚度明显变薄,逆规散光的比率明显增加,循规散光的比率明显减少。

AIM： To understand the changes of corneal thickness and corneal curvature with age increasing through a comparison of them among different age groups. METHODS： 3752 patients （7490 eyes） without corneal ulcer, corneal spot, keratoconus and corneal trauma were picked out from the general community survey from January 2006 to September 2007, then these patients＇ corneal thickness, corneal curvature and axial direction were examined. And the patients are divided into five groups： A,years of 5 - 10,805 patients （1 610 eyes） ; B, years of 11 - 17,535 patients （1 060 eyes） ; C,years of 18 - 40,994 patients （1987 eyes）;D, years of 41 - 59, 723 patients （1445 eyes） ; E, years of 60 - 80, 695 patients （ 1 388 eyes）. RESULTS： The statistical significance about the thickness of corneal existed in the comparisons between group E and the other four groups, and the statistical significance about with-the-rule astigmatism existed in the comparisons among each group（ P〈 0.05）. CONCLUSION： For the old, the corneal thickness will become thin, the ratio of against-the-rule astigmatism will increase and with-the-rule astigmatism will reduce.