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心肌缺血的干细胞移植治疗 被引量：1

Stem Cell Transplantation Therapy on Myocardial Ischemia
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摘要 干细胞移植应用于心肌缺血的临床研究为各种原因引起的缺血性心脏病患者带来了新的希望。虽然目前的研究结果还有待大规模、随机、双盲、对照研究的验证,但学者们在干细胞的纯化鉴定、细胞移植路径及移植时机等方面的不断探索,将逐步为细胞移植治疗在临床的广泛应用扫清障碍,使细胞移植成为治疗缺血性心脏病的有效方法之一。
作者 杜忠东 段超
机构地区 首都医科大学附属北京儿童医院心内科
出处 《实用儿科临床杂志》 CAS CSCD 北大核心 2009年第1期3-5,共3页 Journal of Applied Clinical Pediatrics
基金 首都医学发展基金重点项目资助(2007-2063)
关键词 心脏病 缺血性 干细胞 治疗
分类号 R541 [医药卫生—心血管疾病]
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参考文献13

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二级参考文献1

  • 1Chiu R C，Ann Thorac Surg，1995年，60卷，1218页

共引文献1

同被引文献17

  • 1杨晓凤.干细胞血管新生与糖尿病足[J].中国实用内科杂志,2006,26(9):1319-1321. 被引量：8
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  • 5Sasaki H,Fukuda S,Otani H. Hypoxic precondi-tioning triggers myocardial angiogenesis:a novel approach to enhance contractile functional reserve in rat with myocar-dial infarction[J].{H}Journal of Molecular and Cellular Cardiology,2002,(3):335.
  • 6Hattori R,Matsubara H. Therapeutic angiogenesis for se-vere ischemic heart diseases by autologous bone marrow cells transplantation[J].{H}Molecular and Cellular Biochemistry,2004,(1/2):151.
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  • 8Yin C,Salloum FN,Kukreja RC. A novel role of microR-NA in late preconditioning:upregulation of endothelial ni-tric oxide synthase and heat shock protein 70[J].{H}CIRCULATION RESEARCH,2009,(5):572.
  • 9Yin C,Wang X,Kukreja RC. Endogenous microRNAs in-duced by heat-shock reduce myocardial infarction following ischemia-reperfusion in mice[J].{H}FEBS Letters,2008,(30):4137.
  • 10Cheng Y,Ji R,Yue J. MicroRNAs are aberrantly expressed in hypertrophic heart:do they play a role in car-diac hypertrophy[J].{H}AMERICAN JOURNAL OF PATHOLOGY,2007,(6):1831.

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实用儿科临床杂志
2009年 第1期

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