麻疹的双相移位研究进展

Progress of investigation of biphase displacement of morbidity of measles

近年新生儿、婴儿、成人麻疹患者逐年增加,临床表现一般仍较典型,成年人麻疹患者全身中毒症状较重。麻疹抗体检测结果阳性是主要的诊断依据。麻疹发病的双相移位的机理可能是,免疫保护力不足,婴儿出生时麻疹抗体力低,孕期母传胎的麻疹抗体减弱,母经乳汁传给婴儿的抗体减弱,成人麻疹抗体水平逐年下降。预防措施是怀孕前给予育龄妇女麻疹疫苗接种,鼓励母乳喂养,麻疹疫苗计划免疫适当提前,在成人追加麻疹疫苗的免疫,加强病毒变异的研究等。

At present the morbidity of measles are increasing year by year in neonatus, infan and adult. The clinical manifestation are typical, but measles of adult were severe. The diagnosis were made by the test of antibody. Immunity insufficiency were the mechanism of biphase displacement of morbidity of measles. The chief reason may be the decreaseing of the antibody of measles in pregnant women, and in adult. The countermeasure were considered that the measles vaccine were inoculated in the women before pregnancy, the immunity of measles vaccine shift to an earlier date in the infan, additional of immunity of measles vaccine were carried out in adult.