中药对烧伤患者免疫功能及急性期蛋白的影响

The effects of Chinese medicine herb mixture on cell mediated immune functions and four kinds of acute phase reaction proteins in burn patients

目的观察中药对伤后细胞免疫功能和４种急性期反应蛋白（ＡＲＰ）的作用。方法在过去动物实验的基础上，将中药配伍后用于烧伤患者。结果能使受损严重的患者淋巴细胞增殖反应及白细胞介素２产生能力，得到显著的改善。对伤后患者血中变化的触珠蛋白、前白蛋白、α１酸性糖蛋白和转铁蛋白均有不同程度的影响。

Objective To search for immunomodulators to improve postburn immune function disorder.Method We studied the Chinese medicinal herbs. On the basis of previous data,we prepared a kind of Chinese medicinal herbal mixture and studied its effects in vivo and in vitro. Result The mixture could restore the cell mediated immune response such as the production of interleukin 2 and the T cell proliferative ability, and could also adjust the levels of serum acute phase reaction proteins, i.e, haptoglobin, prealbumin, transferrin and α1 acid glycoprotein. Conclusion The Chinese herbal mixture showed immure regulatory effects on body defence imbalance and also on acute phase reaction proteins in burn patients.